Bristol Myers Squibb: Scientist, Gene Editing Technology

At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through science. In oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.Cell Therapy is one of the most groundbreaking new forms of cancer treatments being studied today. With therapies only in their infancy and BMS s continued investment in our Cell Therapy capabilities, the growth potential of this science, your career, and the ability to help patients are incredible. Process Science & Technology (PS&T) develops manufacturing platforms to enable current and new product formats, increased product control, lower cost, and lower operational complexity. The PS& T organization works to accelerate the development and implementation of novel technologies to CTDO for integration into existing drug product platform processes. Job DescriptionThe Process Science and Technology of Cell Therapy is seeking a collaborative and enthusiastic scientist to join the Gene Editing and Delivery TCoE team for developing novel cellular immunotherapies. The successful candidate will support the gene editing platform development for autologous and allogeneic cell therapy programs. S/he will be an integral part of the multidisciplinary team dedicated for emerging platform and technology development. The position will require experimental design, execution, data collection, data analysis, drafting of technical reports, and presentation of results in the technical team meetings. This role provides great opportunities not only to grow subject matter expertise but also to interact with multiple project teams and cross-functional stakeholders. Duties and ResponsibilitiesDemonstrate ability to effectively work in cross functional teams, meet deadlines and prioritize multiple projects to support IND enabling studiesWork with CMOs and internal functional team to support gene-editing reagent developmentWrite technical reports, including development reports and Standard Operating ProceduresPerform data-driven decision making and troubleshootingPlan strategically to align with higher level goalsWork closely with process development scientists to support at scale gene-editing experimentsTimely report project status and resource/risk analysis to direct management EducationPh.D. in Virology, Immunology, Bio/chemical Engineering, or a related discipline with minimum 2 years of relevant postdoctoral or industrial experience. M.S. in virology, immunology, bio/chemical Engineering, or a related discipline with minimum 8 years of relevant industrial experience. Experience and SkillsStrong expertise in gene editing on human primary T cell or iPSC using CRISPR-Cas9 or related technologies.Experience with viral (lentivirus and AAV) or non-viral gene delivery methods Proficiency in laboratory bench skills such as with nucleic acid (DNA and RNA) purification, multi-color flow cytometry, cell sorting, ddPCR, qPCR, Sanger sequence and next-generation sequencingExtensive experience with developing and optimizing gene-editing reagent.Familiarity with statistical analysis and design of experiments (DoE)Experience with writing technical documents for interdepartmental use and CMOsExperience working with a multi-disciplinary group in a cross-functional environment.Experience with coaching junior membersExcellent communication and interpersonal skills demonstrated in a team environment.Experience with technical project management and leading ad-hoc or small team is a plus. If you want to challenge yourself, accelerate your career, and give new hope to patients, there s no better place than here with our Cell Therapy team. Full of incredible and dedicated team members, those working on CAR-T and other forms of Cell Therapy are transforming patients lives through science. From studying individualized cell lines to making brand new discoveries, this bold and personal discipline allows you to grow your career while making a lasting impact on the field of medicine. Join us today. BMSCART Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or any part of the recruitment process direct your inquiries to …@bms.com. Visit careers.Bms.Com/eeo-accessibility to access our complete Equal Employment Opportunity statement. Associated topics: aseptic technique, drug, histology, immunohematology, kinesiology, microbiology, nutritionist, pharmacy, therapeutic, toxicologist